Drug-Induced Liver Injury due to Biologics and Immune Check Point Inhibitors

Link to article at PubMed

Med Clin North Am. 2023 May;107(3):623-640. doi: 10.1016/j.mcna.2022.12.008. Epub 2023 Feb 20.


Biological agents have in the last two decades become very important therapeutic agents, particularly for the treatment of various autoimmune disorders. The most widely used biologics are the tumor necrosis factor-α (TNF-α) receptor antagonists: infliximab, adalimumab, and etanercept. Other commonly used biological agents are interleukin (IL)-1 receptor antagonist (Anakinra), interleukin (IL)-6 receptor antagonist (tocilizumab), and CD20 surface antigen antagonist (rituximab). The current review will however focus on TNF-α receptor antagonists.

PMID:37001957 | DOI:10.1016/j.mcna.2022.12.008

Leave a Reply

Your email address will not be published. Required fields are marked *