Pathogenic Mechanisms in Thalassemia II: Iron Overload

Link to article at PubMed

Hematol Oncol Clin North Am. 2023 Apr;37(2):353-363. doi: 10.1016/j.hoc.2022.12.006.


Iron overload remains a lethal complication of β-thalassemia and other anemias caused by ineffective erythropoiesis. This review discusses the pathogenetic mechanisms of iron overload in thalassemia, at organismal, cellular, and molecular levels.

PMID:36907608 | DOI:10.1016/j.hoc.2022.12.006

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