Semin Respir Crit Care Med. 2021 Apr;42(2):218-232. doi: 10.1055/s-0041-1723953. Epub 2021 Feb 18.
Important advances in the understanding and management of venous thromboembolism (VTE) have enhanced our ability to diagnose, prevent, and treat VTE. In this narrative review, we discuss how recent advances in the understanding and management of VTE are changing practice, highlight ongoing unmet needs in VTE management, and outline how novel therapeutic targets with little or no influence on hemostasis may help address these unmet needs.