2021 Feb 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–.
Linezolid is a synthetic oxazolidinone antimicrobial drug. It is indicated for gram-positive infections and approved for the treatment of bacterial pneumonia, skin and skin structure infections, and vancomycin-resistant enterococcal (VRE) infections, including infections complicated by bacteremia. Linezolid does not have approval for the treatment of gram-negative infections, catheter-related bloodstream infections, or catheter site infections. Linezolid's main place in therapy is an alternative to vancomycin in inpatient settings. This activity covers linezolid do that members of the interprofessional team can recognize its indications, coverage, contraindications, and adverse event profile to optimally manage patients with infectious disease and exercise appropriate antimicrobial stewardship.