Cirrhotic Cardiomyopathy

Link to article at PubMed

2021 Mar 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–.

ABSTRACT

Cirrhotic cardiomyopathy (CCM) is a type of cardiac dysfunction in patients with cirrhosis without known cardiac disease. First described in 1953, CCM is characterized by an impaired cardiac response to stress, a hyperdynamic circulatory state, both diastolic and systolic dysfunctions, and various electrophysiologic abnormalities (most notably QT prolongation). This disease occurs in up to 50% of patients with cirrhosis, regardless of etiology. Alcohol use disorder and hemochromatosis are additional risk factors in the development of cardiac disease. As CCM manifests under stress, it remains an under-recognized condition, and no standardized treatment regimen has yet been established. A significant improvement, or reversal, of CCM has been noted in patients after liver transplantation.

PMID:32310549 | Bookshelf:NBK556089

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