Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients

Link to article at PubMed

Eur J Clin Microbiol Infect Dis. 2020 Aug 31. doi: 10.1007/s10096-020-04024-1. Online ahead of print.

ABSTRACT

The prevalence and outcomes of patients who had re-activation of coronavirus disease 2019 (COVID-19) after discharge remain poorly understood. We included 126 consecutively confirmed cases of COVID-19 with 2-month follow-up data after discharge in this retrospective study. The upper respiratory specimen using a reverse-transcription polymerase chain reaction test of three patients (71 years [60-76]) were positive within 11-20 days after their discharge, with an event rate of 19.8 (95%CI 2.60-42.1) per 1,000,000 patient-days. Moreover, all re-positive patients were asymptomatic. Our findings suggest that few recovered patients may still be virus carriers even after reaching the discharge criteria.

PMID:32865669 | DOI:10.1007/s10096-020-04024-1

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