Infect Control Hosp Epidemiol. 2020 Aug 24:1-10. doi: 10.1017/ice.2020.434. Online ahead of print.
We describe an approach to the evaluation and isolation of hospitalized persons under investigation (PUIs) for COVID-19 at a large U.S. academic medical center. Only a small proportion (2.9%) of PUIs with one or more repeat SARS-CoV-2 nucleic acid tests (NATs) after a negative NAT were diagnosed with COVID-19 infection.