Cardiac and arrhythmic complications in Covid-19 patients.

Link to article at PubMed

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Cardiac and arrhythmic complications in Covid-19 patients.

J Cardiovasc Electrophysiol. 2020 Apr 09;:

Authors: Kochi AN, Tagliari AP, Forleo GB, Fassini GM, Tondo C

In December 2019, the world started to face a new pandemic situation, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although COVID-19 clinical manifestations are mainly respiratory, major cardiac complications are being reported. Cardiac manifestations etiology seems to be multifactorial, comprising direct viral myocardial damage, hypoxia, hypotension, enhanced inflammatory status, ACE2-receptors downregulation, drug toxicity, endogenous catecholamine adrenergic status, among others. Studies evaluating COVID-19 patients presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon. Besides, drugs currently used to treat the COVID-19 are known to prolong the QT interval and can have a proarrhythmic propensity. This review focus on COVID-19 cardiac and arrhythmic manifestations and, in parallel, makes an appraisal of other virus epidemics as SARS-CoV, MERS-CoV, and H1N1 influenza. This article is protected by copyright. All rights reserved.

PMID: 32270559 [PubMed - as supplied by publisher]

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