No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience.
Open Forum Infect Dis. 2018 Dec;5(12):ofy192
Authors: Box MJ, Ortwine KN, Goicoechea M, Scripps Antimicrobial Stewardship Program (SASP)
We assessed the effectiveness of a Lactobacillus probiotic on rates of health care facility-onset Clostridium difficile infection (HO-CDI) in patients receiving antibiotics. A total of 1576 patients were evaluated. There was no difference in the HO-CDI incidence between those who received probiotics and those who did not (1.8% vs 0.9%; P = .16).
PMID: 30568976 [PubMed]