Prevalence and pROgnostic impact of anemia and IRON deficiency in patients hospitalized in an internal medicine ward: the PRO-IRON Study.
Eur J Haematol. 2017 Sep 08;:
Authors: Fonseca C, Araújo M, Moniz P, Marques F, Araújo I, Costa L, Rodrigues J, Frade L, Botella A, Jesus S, Leitão A, Campos L
OBJECTIVES: To assess prevalence, predictive factors, and prognostic impact on in-hospital mortality of anemia, iron deficiency anemia (IDA), iron deficiency with or without anemia (ID), and iron deficiency without anemia (IDWA) in patients admitted to an internal medicine ward METHODS: This one-year prospective study collected data on demographics, medical history, and blood tests in 771 consecutive patients on admission RESULTS: Most patients were ≥65 years old (80%), and had hypertension (63%), moderate chronic kidney disease (CKD) (43%), and heart failure (41%). Prevalence of anemia, IDA, ID, and IDWA was 67%, 41%, 58%, and 18%, respectively. Anemia was independently associated with age ≥65 years (OR 1.76, 95% CI 1.15-2.70), active cancer (OR 2.44, 95% CI 1.42-4.39), and moderate CKD (OR 1.65, 95% CI 1.12-2.43). ID was independently associated with female gender (OR 2.29, 95% CI 1.64-3.22), heart failure (OR 1.65, 95% CI 1.16-2.37), and moderate CKD (OR 2.95, 95% CI 2.04-4.30). Incidence of in-hospital mortality was 21% and independently associated with anemia (RR 1.82, 95% CI 1.21-2.74) CONCLUSIONS: Anemia and iron deficiency were highly prevalent in internal medicine patients. As anemia negatively impacts on in-hospital mortality, awareness should be raised for effective diagnosis and management of these comorbidities in hospitalized patients. This article is protected by copyright. All rights reserved.
PMID: 28885736 [PubMed - as supplied by publisher]