Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of One Fatal and One Surviving Case.
Clin Infect Dis. 2015 Dec 17;
Authors: Cope JR, Conrad DA, Cohen N, Cotilla M, Dasilva A, Jackson J, Visvesvara G
Abstract
Primary amebic meningoencephalitis (PAM) is a fulminant central nervous system infection caused by the thermophilic free-living ameba Naegleria fowleri. Few survivals have been documented and adequate treatment is lacking. We report two PAM cases, one fatal and one surviving, treated with the novel antiparasitic agent miltefosine.
PMID: 26679626 [PubMed - as supplied by publisher]