Higher Incidence of Acute Kidney Injury (AKI) With Intravenous Colistin (Colistimethate Sodium) Compared to PB (Polymyxin B) in Critically Ill Patients at a Tertiary Care Medical Center.

Link to article at PubMed

Higher Incidence of Acute Kidney Injury (AKI) With Intravenous Colistin (Colistimethate Sodium) Compared to PB (Polymyxin B) in Critically Ill Patients at a Tertiary Care Medical Center.

Clin Infect Dis. 2013 Jul 9;

Authors: Akajagbor D, Wilson S, Shere-Wolfe KD, Dakum P, Charurat M, Gilliam BL

Abstract
Nephrotoxicity was assessed in 173 critically ill patients receiving intravenous colistin or PB and occurred in 60.4% and 41.8%, respectively. Further investigation is necessary to elucidate the reason for the difference in nephrotoxicity observed between the groups as well as to assess the impact of severity of illness and dosing/administration.

PMID: 23840000 [PubMed - as supplied by publisher]

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