The accuracy of the INR and the ACCP recommendations on the use of vitamin K to reverse over anticoagulation.
J Thromb Haemost. 2012 Aug 10;
Authors: Tripodi A, Moia M
We read with interest the 2012 evidence-based management of anticoagulant therapy on clinical practice guidelines of the American College of Chest Physicians (ACCP), published recently in Chest . When discussing on how and when using vitamin K to reverse over anticoagulation, the guidelines recommended: (a) "for patients taking VKAs with an INR between 4.5 and 10 and with no evidence of bleeding, we suggest against the routine use of vitamin K (Grade 2B)". (b) "for patients taking VKAs with INR>10.0 and with no evidence of bleeding, we suggest that oral vitamin K be administered (Grade 2C)". © 2012 International Society on Thrombosis and Haemostasis.
PMID: 22882756 [PubMed - as supplied by publisher]