About fACE: Peri-Operative Use of ACE Inhibitors.
Circulation. 2012 Jun 19;
Authors: Barodka V, Nyhan D, Berkowitz D
Since the introduction of the first Angiotensin-converting enzyme inhibitor (ACEI) captopril in 1981, ACE inhibitors have become a mainstay of anti-hypertensive therapy. In addition to lowering BP, there is overwhelming evidence that ACE inhibitors (and angiotensin-receptor blockers (ARB)) provide end organ protection independent of blood their pressure lowering properties in diseases such as CHF, post MI, diabetes, and renal insufficiency.(1) It is an unresolved issue, however, if ACE inhibitors have a protective or deleterious effect on perioperative outcomes(2).(SELECT FULL TEXT TO CONTINUE).
PMID: 22715474 [PubMed - as supplied by publisher]