Antimicrobial Prescribing Practices in Response to Different Clostridium difficile Diagnostic Methodologies.
Infect Control Hosp Epidemiol. 2011 Nov;32(11):1133-6
Authors: Sydnor ER, Lenhart A, Trollinger B, Avdic E, Maragakis LL, Carroll KC, Cosgrove SE
We evaluated treatment decisions and antimicrobial use related to 2 testing algorithms for Clostridium difficile infection (CDI). Our findings suggest that a 2-step testing algorithm using rapid polymerase chain reaction confirmatory testing leads to decreased unnecessary anti-CDI antimicrobial use. In addition, a significant proportion of patients with confirmed CDI were not treated according to recommended guidelines.
PMID: 22011545 [PubMed - in process]