Imaging findings in a fatal case of pandemic swine-origin influenza A (H1N1).
AJR Am J Roentgenol. 2009 Dec;193(6):1500-3
Authors: Mollura DJ, Asnis DS, Crupi RS, Conetta R, Feigin DS, Bray M, Taubenberger JK, Bluemke DA
OBJECTIVE: Although most cases of swine-origin influenza A (H1N1) virus (S-OIV) have been self-limited, fatal cases raise questions about virulence and radiology's role in early detection. We describe the radiographic and CT findings in a fatal S-OIV infection. CONCLUSION: Radiography showed peripheral lung opacities. CT revealed peripheral ground-glass opacities suggesting peribronchial injury. These imaging findings raised suspicion of S-OIV despite negative H1N1 influenza rapid antigen test results from two nasopharyngeal swabs; subsequently, those results were proven to be false-negatives by reverse transcriptase polymerase chain reaction. This case suggests a role for CT in the early recognition of severe S-OIV.
PMID: 19933640 [PubMed - indexed for MEDLINE]