Pulmonary Embolism in COVID-19 Pneumonia: Random Association or Causality?

Link to article at PubMed

Cureus. 2020 Jun 29;12(6):e8900. doi: 10.7759/cureus.8900.


Coronavirus disease 2019 (COVID-19) is an ongoing pandemic. COVID-19 leads to a plethora of clinical syndromes, most commonly affecting the pulmonary system but also the cardiovascular, hematologic, and gastrointestinal systems. There is emerging evidence of an association between COVID-19 and venous thromboembolism (VTE). In this report, we have discussed three cases with a COVID-19 infection, whose clinical course was complicated by the presence of pulmonary embolism (PE) without evident risk factors for VTE. All three patients presented with hypoxia and were found to have elevated D-dimer levels. Subsequently, the patients underwent computed tomography (CT) angiography of the chest, which confirmed the presence of pulmonary embolism. Anticoagulation was initiated per guidelines. There is a need to have a low threshold for suspecting pulmonary embolism in patients with COVID-19 infection who present with a sudden onset of severe hypoxia. There is a dire need to increase awareness among health care providers regarding this manifestation of the virus.

PMID:32742867 | PMC:PMC7389163 | DOI:10.7759/cureus.8900

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