Impella use in acute myocardial infarction complicated by cardiogenic shock and cardiac arrest : Analysis of 10 years registry data.

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Impella use in acute myocardial infarction complicated by cardiogenic shock and cardiac arrest : Analysis of 10 years registry data.

Resuscitation. 2019 Apr 19;:

Authors: Davidsen C, Packer EJS, Løland KH, Rotevatn S, Nygreen EL, Eriksen E, Øksnes A, Herstad J, Haaverstad R, Bleie Ø, Tuseth V

Abstract
AIMS: To assess characteristics and outcome of patients treated with Impella for acute myocardial infarction (AMI) complicated by severe cardiogenic shock (CS) or cardiac arrest (CA).
METHODS AND RESULTS: From 2008 through 2017, 92 patients with AMI complicated by CS were treated with Impella. Survival varied according to clinical presentation. Patients in cardiogenic shock without CA had a 75% 30-day survival. Patients with CA and return of spontaneous circulation (ROSC) had a 43% survival and those with CA and ongoing cardio-pulmonary resuscitation (CPR) had a 6% 30-day survival. Age, pre-existing hypertension, coronary disease, ventilatory support and use of adrenergic agents were associated with worse prognosis. Complications were predominantly access site related.
CONCLUSIONS: In this registry of patients with AMICS treated with Impella, hypertension and older age were found to be negatively predictive for survival. Patients without CA had the highest 30-day survival. In patients with ROSC, survival was strongly related to age and comorbidity. Patients with ongoing CPR had very high mortality.

PMID: 31009694 [PubMed - as supplied by publisher]

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