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Carbapenem De-escalation Therapy in a Resource-Limited Setting.
Infect Control Hosp Epidemiol. 2013 Dec;34(12):1310-3
Authors: Apisarnthanarak A, Bhooanusas N, Yaprasert A, Mundy LM
Abstract
Pulmonary infection ([Formula: see text]) and an infectious diseases consultation ([Formula: see text]) were associated with carbapenem de-escalation; pulmonary infection and septic shock were associated with unsuccessful de-escalation. Successful de-escalaltion was associated with lower mortality (0% vs 23%; [Formula: see text]) and shorter duration of carbapenem use (4 vs 10 days; [Formula: see text]).
PMID: 24225617 [PubMed - in process]