Neutropenia and antibiotics: when, what, how and why?

Link to article at PubMed

Curr Opin Infect Dis. 2023 Aug 1;36(4):218-227. doi: 10.1097/QCO.0000000000000932. Epub 2023 Jun 12.

ABSTRACT

PURPOSE OF REVIEW: Our aim is to review recent literature on antibiotic use in patients with neutropenia.

RECENT FINDINGS: Prophylactic antibiotics are associated with risks and have limited mortality benefit. While early antibiotic use in febrile neutropenia (FN) is critical, early de-escalation or discontinuation may be safe in many patients.

SUMMARY: With an increasing understanding of potential risks and benefits of use and improved risk assessment, paradigms of antibiotic use in neutropenic patients are changing.

PMID:37431552 | DOI:10.1097/QCO.0000000000000932

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