Screening for ocular candidiasis among patients with candidemia: Is it time to change practice?

Link to article at PubMed

Clin Infect Dis. 2022 Mar 24:ciac233. doi: 10.1093/cid/ciac233. Online ahead of print.


Ocular candidiasis (OC) complicates ~10% of candidemia and carries potentially severe morbidity. There are conflicting recommendations about the need for routine funduscopic examinations of candidemic patients. Indirect funduscopy is accurate and safe in diagnosing OC, and positive findings change recommended treatment. However, conclusive evidence is lacking that treatment changes improve outcomes. Bringing perspectives as infectious diseases physicians and ophthalmologists, we review controversies about OC and endorse routine screening during candidemia. We acknowledge difficulties in obtaining inpatient ophthalmologic consults, and recommend studies evaluating digital fundus photography and tele-ophthalmology as an alternative to funduscopic examinations by ophthalmologists in asymptomatic patients.

PMID:35325089 | DOI:10.1093/cid/ciac233

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