Am J Gastroenterol. 2022 Jan 12. doi: 10.14309/ajg.0000000000001608. Online ahead of print.
ABSTRACT
INTRODUCTION: Rifaximin use in combination with lactulose is associated with a decreased risk of overt hepatic encephalopathy (HE).
METHODS: We prospectively evaluated the impact of an interruptive electronic medical record alert to indicate rifaximin for patients with cirrhosis and HE on lactulose.
RESULTS: The intervention was associated increased rifaximin utilization, particularly for nongastroenterology and hospitalist services odds ratio 1.20 95% confidence interval (1.09-1.31). For patients with HE, the intervention was associated with a lower readmission risk-adjusted subdistribution hazard ratio 0.63 95% confidence interval (0.48-0.82).
DISCUSSION: An interruptive alert in the electronic ordering system was associated with a lower risk of readmissions.
PMID:35020619 | DOI:10.14309/ajg.0000000000001608