?ALB level and COVID-19Dynamic change of serum albumin level can predict the prognosis of COVID-19 patients with hypoalbuminemia

J Med Virol. 2021 Nov 9. doi: 10.1002/jmv.27439. Online ahead of print.

ABSTRACT

Hypoalbuminemia usually predicts higher mortality, longer hospital stay, and more frequent re-admission¹ . About 40%-60% of COVID-19 patients develop hypoalbuminemia at admission^{2, 3} . This may be due to an increase of capillary permeability caused by systemic inflammatory response⁴ , which leads to the leakage of serum albumin into interstitial space⁵ , poor nutritional status, and impaired liver function¹ . COVID-19 patients with hypoalbuminemia are more severe and/or critical² , and have a higher probability of intensive care unit (ICU) admission and higher risk of death^{6, 7} . However, few studies have evaluated the dynamic change of serum albumin level in COVID-19 patients with hypoalbuminemia on the patients' death. This article is protected by copyright. All rights reserved.

PMID:34750829 | DOI:10.1002/jmv.27439