Kidney damage in COVID-19

Link to article at PubMed

Nephrol Ther. 2021 Jun 23:S1769-7255(21)00138-3. doi: 10.1016/j.nephro.2021.06.002. Online ahead of print.

ABSTRACT

COVID-19 is a disease caused by the RNA virus SARS-CoV-2. It is characterised by an attack mainly affecting the respiratory system. There is renal involvement which is characterised by three main types of damage, acute tubular necrosis occurring in the most severe cases, proximal tubulopathy which is a prognostic marker of the disease and segmental and focal hyalinosis occurring in a genetically predisposed terrain. The pathophysiology of SARS-CoV-2 renal involvement is not yet defined. The direct role of the virus is debated, whereas the cytokine storm and the hypoxic and thrombotic complications seem more important. The long-term outcome of the renal damage appears to be quite good. Long-term follow-up will allow us to say whether the renal damage is part of the long COVID.

PMID:34266783 | DOI:10.1016/j.nephro.2021.06.002

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