Prognostic accuracy of Quick SOFA in older adults hospitalized with community acquired urinary tract infection

Link to article at PubMed

Int J Clin Pract. 2021 Jul 9:e14620. doi: 10.1111/ijcp.14620. Online ahead of print.

ABSTRACT

INTRODUCTION: Quick [Sepsis-related] Sequential Organ Failure Assessment (qSOFA) is a prognostic score based on sepsis-3 definition, easy to carry out, whose application has been studied in older adults with sepsis from different sources and respiratory sepsis. However, to date no study has analyzed its prognostic accuracy in older adults admitted to hospital with community urinary tract infection.

METHODS: In a prospective study of 282 older adults admitted to hospital with community acquired urinary tract infection, the application of qSOFA to predict hospital mortality was analyzed. The predictive capacity of qSOFA for in-hospital mortality was compared with Systemic Inflammatory Response Syndrome score (SIRS) and Sequential Organ Failure Assessment (SOFA), which require laboratory test in order to be calculated.

RESULTS: In a population with a median age of 81 years, where 51.8% were males and 10.6% had septic shock, qSOFA showed sensibility and specificity of 88.46 and 75.78% and area under the receiver operating characteristic curves (AUROC) of 0.810. AUROC for qSOFA was significantly higher than that of SIRS (AUROC 0.597, p = 0.005) and with no statistical differences with SOFA (AUROC 0.841, p = 0.635).

CONCLUSION: qSOFA showed a better predictive prognostic accuracy than SIRS and similar to SOFA in older adults admitted to hospital with community acquired urinary tract infection, having the advantage of not requiring laboratory tests.

PMID:34240521 | DOI:10.1111/ijcp.14620

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