Lung Ultrasound to Diagnose Pulmonary Congestion Among Patients on Hemodialysis: Comparison of Full Versus Abbreviated Scanning Protocols

Link to article at PubMed

Am J Kidney Dis. 2021 May 27:S0272-6386(21)00632-6. doi: 10.1053/j.ajkd.2021.04.007. Online ahead of print.

ABSTRACT

RATIONALE & OBJECTIVE: Pulmonary congestion contributes to morbidity and mortality in patients with kidney failure on hemodialysis, but physical assessment is an insensitive approach to its detection. Lung ultrasound is useful for assessing the presence and severity of pulmonary congestion, but the most widely validated 28-zone study is cumbersome. We sought to compare abbreviated 4-, 6-, and 8-zone studies to 28-zone studies.

STUDY DESIGN: Diagnostic test study.

SETTING & PARTICIPANTS: Convenience sample of 98 patients with kidney failure on hemodialysis presenting to an emergency department in the United States.

TESTS COMPARED: 4, 6, and 8-zone lung ultrasound studies versus a 28-zone lung ultrasound.

OUTCOMES: Prediction of pulmonary congestion and 30-day mortality.

RESULTS: All patients completed a 28-zone lung ultrasound. Correlation coefficients (non-parametric Spearman) between each of the studies were high (all values >0.84). Bland-Altman analysis showed good agreement. Each of the short-form studies discriminated well with area under the receiver-operator characteristic curve >0.83 for no-to-mild versus moderate-to-severe pulmonary congestion. During a median follow-up of 778 days, 46 (47%) died. Patients with moderate-to-severe pulmonary congestion on lung ultrasound had a 30-day mortality rate similar to that observed among patients with no-to-mild pulmonary congestion (OR 0.95 ,95% CI 0.70-1.29).

LIMITATIONS: Single-center study conducted in emergency care setting, convenience sample of patients and lack of long-term follow-up data.

CONCLUSIONS: Among hemodialysis patients presenting to an emergency department, 4, 6, or 8-zone lung ultrasounds were comparable to 28-zone studies for the assessment of pulmonary congestion. Mortality rates did not differ between those with no-to-mild and moderate-to-severe pulmonary congestion.

PMID:34090905 | DOI:10.1053/j.ajkd.2021.04.007

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