Management of Connective Tissue Disease-Associated Interstitial Lung Disease

Link to article at PubMed

Clin Chest Med. 2021 Jun;42(2):295-310. doi: 10.1016/j.ccm.2021.03.010.


The presence of interstitial lung disease (ILD) negatively affects prognosis among patients with an underlying connective tissue disease (CTD). The initial approach to care should determine whether the CTD-ILD needs pharmacologic treatment or not. There is little direct evidence to guide who and how to treat. At present, any severe, active, and/or progressive ILD should be pharmacologically treated. Immunosuppressants and/or corticosteroids are the mainstay of pharmacologic therapy for all CTD-ILDs, whereas antifibrotics may be beneficial in some scenarios. A comprehensive and multidisciplinary approach to management is also an important aspect of patient care.

PMID:34024405 | DOI:10.1016/j.ccm.2021.03.010

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