Liver and Gastrointestinal Involvement: Update

Link to article at PubMed

Hematol Oncol Clin North Am. 2020 Dec;34(6S):e1-e13. doi: 10.1016/j.hoc.2020.11.001. Epub 2020 Dec 31.


The organs affected most commonly by AL amyloidosis are the kidneys and heart, however, liver and gastrointestinal (GI) tract are also commonly affected. Symptoms of GI amyloidosis often mimic those of other GI disorders; having a keen awareness of the need to evaluate for amyloidosis is critical in avoiding delay in diagnosis and intervention. GI and liver involvement is associated with significant complications, and challenges in symptomatic management. As with all AL-related organ disease, early systemic treatment can prevent progression of tissue damage and improve outcomes.

PMID:33518015 | DOI:10.1016/j.hoc.2020.11.001

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