2021 May 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–.
Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. It is in the nitrate class of drugs. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced ejection fraction, and achalasia. This activity will highlight the mechanism of action, adverse event profile, off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions pertinent for members of the health care team in managing patients with angina pectoris due to coronary artery disease and related conditions.