Heparin Induced Thrombocytopenia

Link to article at PubMed

2021 Oct 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–.


Heparin-induced thrombocytopenia (HIT) is a severe complication that can occur in patients exposed to any form or amount of heparin products. A fall in platelet counts and a hypercoagulable state characterize HIT. Patients who experience HIT may also develop thromboembolic complications that are associated with morbidity and mortality. This is a significant burden since heparin is widely used for treatment and prophylaxis of thromboembolism, line flushes, and heparin-coated catheters. This review will discuss the pathophysiology, diagnosis, and management of patients with HIT.

PMID:29493955 | Bookshelf:NBK482330

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