Link to article at PubMed

2020 Dec 15. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–.


Cephalexin is an antibiotic that is effective against most gram-positive cocci. Additionally, cephalexin is effective against gram-negative bacteria, particularly E. coli, Proteus mirabilis, and Klebsiella pneumonia. Cephalexin indications include for treatment in acute and chronic urinary tract infections, gonorrhea, upper and lower respiratory tract infections, scarlet fever, beta-lactamase-producing staphylococcal infections, and streptococcal septicemia. Cephalexin is also commonly used in treating streptococcal and staphylococcal skin infections. Additionally, cephalexin can also be given before and following surgical operations to decrease the risk of surgical site infections, especially in patients that are having a cesarean section.

PMID:31747187 | Bookshelf:NBK549780

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