Biomarkers in acute respiratory distress syndrome

Link to article at PubMed

Curr Opin Crit Care. 2021 Feb 1;27(1):46-54. doi: 10.1097/MCC.0000000000000786.

ABSTRACT

PURPOSE OF REVIEW: This article provides an overview of protein biomarkers for acute respiratory distress syndrome (ARDS) and their potential use in future clinical trials.

RECENT FINDINGS: The protein biomarkers studied as indices of biological processes involved in the pathogenesis of ARDS may have diagnostic and/or prognostic value. Recently, they also proved useful for identifying ARDS phenotypes and assessing heterogeneity of treatment effect in retrospective analyses of completed clinical trials.

SUMMARY: This article summarizes the current research on ARDS biomarkers and provides insights into how they should be integrated as prognostic and predictive enrichment tools in future clinical trials.

PMID:33278123 | PMC:PMC7774234 | DOI:10.1097/MCC.0000000000000786

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