Pathogenesis guided therapeutic management of COVID-19: an immunological perspective

Link to article at PubMed

Int Rev Immunol. 2020 Oct 28:1-18. doi: 10.1080/08830185.2020.1840566. Online ahead of print.


Lack of standardized therapeutic approaches is arguably the significant contributor to the high burden of mortality observed in the ongoing pandemic of the Coronavirus disease, 2019 (COVID-19). Evidence is accumulating on SARS-CoV-2 specific immune cell dysregulation and consequent tissue injury in COVID-19. Currently, no definite drugs or vaccines are available against the disease; however initial results of the ongoing clinical trials have raised some hope. In this article, taking insights from the emerging empirical evidence about host-virus interactions, we deliberate upon plausible pathogenic mechanisms and suitable therapeutic approaches for COVID-19.

PMID:33111578 | DOI:10.1080/08830185.2020.1840566

Leave a Reply

Your email address will not be published. Required fields are marked *