Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group

Link to article at PubMed

Med Clin (Engl Ed). 2020 Sep 26. doi: 10.1016/j.medcle.2020.06.013. Online ahead of print.


BACKGROUND: SARS-CoV-2 infection is clinically very heterogeneous, varying from asymptomatic to severe clinical conditions with a fatal outcome. Some studies suggests that the ABO blood group could be a biological marker of susceptibility for the development of the disease.

MATERIAL AND METHODS: We collected data from patients admitted with COVID-19 infection who had ABO blood group recorded, and analyzed the incidence by groups, compared with the global population in Navarre, as well as their main complications and evolution.

RESULTS: Group O was proportionally less represented in the hospitalized patients with respect to the global population, although the difference was not statistically significant. Group B had significantly higher rates of thrombotic complications and required more admissions in intensive care units.

CONCLUSION: The study suggests a lower susceptibility to infection in group O and a higher risk of complications in group B. Studies with a larger sample size are required in order to obtain significant results.

PMID:33015369 | PMC:PMC7519708 | DOI:10.1016/j.medcle.2020.06.013

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