Eur Respir J. 2020 Jul 16:2002113. doi: 10.1183/13993003.02113-2020. Online ahead of print.
ABSTRACT
BACKGROUND: Use of existing disease severity scores would greatly contribute to risk stratification and rationally resource allocation in COVID-19 pandemic. However, the performance of these scores in COVID-19 hospitalised patients with pneumonia was still unknown.
METHODS: In this single center, retrospective study, all hospitalised patients with COVID-19 pneumonia from Wuhan Jin Yin-tan Hospital who had discharged or died as of February 15, 2020 were enrolled. Performance of PSI, CURB-65, A-DROP, CRB-65, SMART-COP, qSOFA and NEWS2 were validated. Net reclassification improvement (NRI) and integrated discrimination improvement (IDI) were also estimated.
RESULTS: Among the 654 patients enrolled, 133 patients died and 521 were discharged. Areas of under curves (AUCs) of A-DROP, CURB-65, PSI, SMART-COP, NEWS2, CRB-65 and qSOFA in the prediction of in-hospital death were 0.87, 0.85, 0.85, 0.84, 0.81, 0.80 and 0.73 respectively.
CONCLUSION: ADROP is a reliable tool for risk stratification of death in COVID-19 hospitalised patients on admission.
PMID:32675205 | DOI:10.1183/13993003.02113-2020