Hydroxychloroquine and Covid-19: A Cellular and Molecular Biology Based Update

Link to article at PubMed

Pal A, et al. Indian J Clin Biochem 2020 - Review.

ABSTRACT

As the time for finding a definitive and safe cure as a vaccine for novel Corona Virus Disease 2019 (Covid-19) is still far, there is need to study in depth about the other potential drugs, which can save millions of lives due to Covid-19 pandemic. Right at the center of the debate is the use of drug "Hydroxychloroquine" as a prophylaxis as well as a treatment strategy against Covid-19 in conjunction with azithromycin. In this review, we will study the cellular and molecular aspects of hydroxychloroquine, which had driven its use in Covid-19 patients, as well as its chemistry and pharmacokinetics along with clinical trials going on worldwide using hydroxychloroquine against Covid-19.

PMID:32641874 | PMC:PMC7286553 | DOI:10.1007/s12291-020-00900-x

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