Allez M, et al. Arthritis Rheumatol 2020.
ABSTRACT
IgA vasculitis is a systemic small-vessel vasculitis which may be triggered by different microorganisms. IgA vasculitis cases have been reported in patients with immune-mediated inflammatory disorders treated with TNF inhibitors. Here we report the case of a young Crohn's disease patient in clinical remission under adalimumab admitted for an IgA vasculitis, with an extended ileitis, and a positive PCR testing for Covid-19. Serum IgA levels were markedly increased and serology for Covid-19 was weakly positive for IgA. Even if we cannot prove the causality of Covid-19, it is remarkable to note that this case of IgA vasculitis was associated with high IgA levels in the serum and the Covid-19 serology was positive only for IgA.
PMID:32633104 | DOI:10.1002/art.41428