Lipase Elevation in Patients With COVID-19

Link to article at PubMed

McNabb-Baltar J, et al. Am J Gastroenterol 2020.

ABSTRACT

INTRODUCTION: Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19.

METHODS: A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19.

RESULTS: Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms.

DISCUSSION: Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.

PMID:32496339 | PMC:PMC7288768 | DOI:10.14309/ajg.0000000000000732

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