The many faces of the anti-COVID immune response.
J Exp Med. 2020 06 01;217(6):
Authors: Vardhana SA, Wolchok JD
The novel 2019 strain of coronavirus is a source of profound morbidity and mortality worldwide. Compared with recent viral outbreaks, COVID-19 infection has a relatively high mortality rate, the reasons for which are not entirely clear. Furthermore, treatment options for COVID-19 infection are currently limited. In this Perspective, we explore the contributions of the innate and adaptive immune systems to both viral control as well as toxicity during COVID-19 infections and offer suggestions to both understand and therapeutically modulate anti-COVID immunity.
PMID: 32353870 [PubMed - indexed for MEDLINE]