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COVID-19 in a patient with long-term use of glucocorticoids: A study of a familial cluster.
Clin Immunol. 2020 Apr 07;:108413
Authors: Han Y, Jiang M, Xia D, He L, Lv X, Liao X, Meng J
Abstract
Clusters of patients with novel coronavirus disease 2019 (COVID-19) have been successively reported globally. Studies show clear person-to-person transmission. The average incubation period is 2-14 days, and mostly 3-7 days. However, in some patients, this period may be longer. Here, we report a familial cluster of COVID-19 where a 47-year-old woman with long-term use of glucocorticoids did not develop any symptoms within the 14-day quarantine period but was confirmed with COVID-19 by tested positive of antibody on day 40 after she left Wuhan. Almost at the same time, her father and sister were diagnosed with COVID-19. The results suggest that the long-term use of glucocorticoids might cause atypical infections, a long incubation period, and extra transmission of COVID-19.
PMID: 32276139 [PubMed - as supplied by publisher]