Correlation between the glucose level and the development of acute pancreatitis.
Saudi J Biol Sci. 2019 Feb;26(2):427-430
Authors: Sun YF, Song Y, Liu CS, Geng JL
Objective: To investigate the correlation between the level of glucose in serum and the development of acute pancreatitis (AP).
Methods: Data of 153 AP cases were collected, in which there were 130 patients with mild AP (MAP), 4 with moderate-severe AP (MSAP) and 19 with severe AP (SAP). At the time of admission, following indexes of patients were recorded: glucose, APACHE II score, TNF-α and C-reaction protein (CRP).
Results: At the time of admission, the levels of glucose in serum and APACHE II scores in the MSAP and SAP groups were significantly higher than those in the MAP group, but after treatment, the level of glucose in serum was recovered in 95.8% of the patients in the MAP group, while this digit in the SAP group remained to be 68.4%; in the SAP group, the levels of TNF-α and CRP in patients with sustained hypertension were significantly higher than those with non-persistent hypertension; in terms of the length of stay in hospital, the SAP group was shorter than that in the non-treatment group, and the difference had statistical significance (p < 0.05). Moreover, we found that the level of glucose in serum was positively correlated with the APACHE II scores, TNF-α and CRP.
Conclusion: Glucose level in serum can be used as one of the indicators for evaluating the severity and development of AP in clinical practice.
PMID: 31485188 [PubMed]