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Trends of opioid use disorder amongst hospitalized patients with chronic pain.
Pain Pract. 2019 May 11;:
Authors: Orhurhu V, Olusunmade M, Urits I, Viswanath O, Peck J, Orhurhu MS, Adekoya P, Hirji S, Sampson J, Simopoulos T, Jatinder G
Abstract
BACKGROUND: Chronic pain patients managed with opioids are at an increased risk of opioid misuse or opioid use disorder (OUD). In recent years, there has seen a stark increase in abuse, misuse, and diversion of prescription opioid medications. The aim of this study is to investigate trends in changing rates of opioid use disorder amongst chronic pain patients.
METHODS: The National Inpatient Sample (NIS) database identified chronic pain admissions with OUD from 2011 - 2015. Patients were identified from the NIS database using International Classification of Diseases, Ninth and Tenth diagnosis codes for chronic pain and OUD. Annual estimates and trends were determined for OUD, patient characteristics, OUD amongst subgroups of chronic pain conditions, and discharge diagnosis.
RESULTS: We identified 10.3 million patients with chronic pain. Of this, 680,631 patients were diagnosed with OUD. OUD increased from 109,222 in 2011 to 172,680 in 2015 (P<0.001). Similarly, there was upward trends of OUD among females (53.2% to 54.5%; P=0.09), patients aged 65 - 84 years (11.8% to 17%;P<0.001), Medicare insured patients (39.5% to 46.0%; P<0.01), patients with low annual household income (27.8% to 33.3%; P<0.001), and cannabinoid use disorder (CUD) (7.2% to 8.3%; P=0.01). OUD increased from 2011 to 2015 in patients with chronic regional pain syndrome (5.53% to 7.46%;P=0.01) and spondylosis (1.32% to 1.81%; P<0.001).
CONCLUSIONS: These findings suggest that OUD increased substantially from 2011 to 2015. Disparities of OUD with increasing use among vulnerable populations including women, those with Medicare insurance, tobacco use disorder, and low annual income should be explored further. This article is protected by copyright. All rights reserved.
PMID: 31077526 [PubMed - as supplied by publisher]