Efficacy and accuracy of qSOFA and SOFA scores as prognostic tools for community-acquired and healthcare-associated pneumonia.
Int J Infect Dis. 2019 Apr 24;:
Authors: Asai N, Watanabe H, Shiota A, Kato H, Sakanashi D, Hagihara M, Koizumi Y, Yamagishi Y, Suematsu H, Mikamo H
BACKGROUND: The Japanese Respiratory Society recently updated the prognostic guidelines for pneumonia, recommending that pneumonia severity be evaluated using the Sequential Organ Failure Assessment (SOFA) and the quick SOFA (qSOFA) in a flow-chart of therapeutic strategy. However, the efficacy and accuracy of these tools are still unknown.
METHODS: All patients with community-acquired pneumonia (CAP) and healthcare-associated pneumonia (HCAP) who were admitted to our institute between 2014 and 2017 were enrolled in this study. On admission, pneumonia severity was evaluated by A-DROP, CURB-65, PSI, I-ROAD, qSOFA, and SOFA. Prognostic factors for 30-day mortality were also analyzed.
RESULTS: This study included 406 patients, 257 males (63%) and 149 females (37%). The median age was 79 years (range, 19-103 years). The 30-day and in-hospital mortality were each 5%. With respect to the diagnostic values of the predictive assessments for 30-day mortality, the area under the receiver-operating characteristic curve (AUROC) value for SOFA score was 0.769 and 0.774 for CAP and HCAP patients, respectively. Further, the AUROC value for SOFA score in CAP and HCAP patients with a qSOFA score≥2 was 0.829 and 0.784, respectively, for 30-day mortality.
CONCLUSIONS: qSOFA and SOFA scores were able to correctly evaluate the severity of CAP and HCAP.
PMID: 31028877 [PubMed - as supplied by publisher]