Predictors of Mortality and Length of Stay in Patients with Hospital-Acquired Clostridioides difficile Infection: A Population-Based Study in Alberta, Canada.
J Hosp Infect. 2019 Apr 13;:
Authors: Leal J, Ronksley P, Henderson EA, Conly J, Manns B
In a population-based, 5-year retrospective cohort study of 5304 adult patients with hospital-acquired Clostridioides difficile infection across Alberta (n=101 hospitals), 30-day all-cause and attributable mortality were 12.2% and 4.5%, respectively. Patients >75 years had the highest odds of attributable mortality (OR 9.34, 95% CI 2.92-29.83) and largest difference in mean length of stay (11.7 days, 95% CI 8.2-15.2). A novel finding was elevated white blood cell count at admission was associated with reduced attributable mortality (OR 0.67, 95% CI 0.50-0.90) which deserves further study. Advancing age was incrementally and significantly associated with all outcomes.
PMID: 30991081 [PubMed - as supplied by publisher]