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ZTI-01 (fosfomycin for injection) in the treatment of hospitalized patients with complicated urinary tract infections.
Future Microbiol. 2019 Mar 11;:
Authors: Burgos RM, Rodvold KA
Abstract
Fosfomycin is a bactericidal antibiotic available since the 1970s whose intravenous formulation has been available in many countries outside the USA. Given the rise in drug resistant bacteria, its introduction into the US market has become a necessity for addressing these organisms. This review provides an overview of the microbiology, clinical pharmacology and initial clinical experiences of the intravenous fosfomycin product (ZTI-01) that is undergoing clinical development in the USA for the treatment of complicated urinary tract infections and acute pyelonephritis.
PMID: 30854892 [PubMed - as supplied by publisher]