Impact of Atrial Fibrillation on patients hospitalized for Acute Myocarditis: Insights from a nationally-representative United States cohort.
Clin Cardiol. 2018 Oct 03;:
Authors: Subahi A, Akintoye E, Yassin AS, Abubakar H, Adegbala O, Mishra T, Abdelrahman M, Shokr M, Afonso L
BACKGROUND: Atrial fibrillation (AF) is associated with increased all-cause mortality in the general population. However, the impact of atrial fibrillation on the in-hospital outcomes of acute myocarditis patients is not well characterized.
METHODS: Patients (age ≥18 years) with a primary diagnosis of acute myocarditis in the National Inpatient Sample (NIS) from 2007 to 2014 were included, using the ICD-9-CM diagnostic codes. We compared the in-hospital outcomes between the AF group and propensity score-matched control group without AF.
RESULTS: AF was reported in 602 (9%) of the acute myocarditis patients. Compared to those without AF, acute myocarditis patients with AF experienced higher in-hospital mortality (odds ratio [OR] 1.7, 95% CI 1.1 to 2.7, p = 0.02). AF was associated with higher risk of cardiogenic shock (OR 1.9, 95% CI 1.3 to 2.8, p < 0.001), cardiac tamponade (OR 5.6, 95% CI 1.2 to 25.3, p = 0.002) and acute kidney injury (1.6, 95% CI 1.1 to 2.1, p = 0.02). Furthermore, patients with AF were more likely to have non-routine hospital discharge (31.6% Vs. 38.4% p = 0.02), longer length of stay and higher cost of hospitalization.
CONCLUSIONS: AF was associated with increased risk of in-hospital mortality and complications in patients admitted to the hospital with acute myocarditis.
PMID: 30284301 [PubMed - as supplied by publisher]