Relation between lymphocyte to monocyte ratio and short-term mortality in patients with acute pulmonary embolism.
Clin Respir J. 2018 Feb;12(2):580-586
Authors: Ertem AG, Yayla C, Acar B, Kirbas O, Unal S, Uzel Sener M, Akboga MK, Efe TH, Sivri S, Sen F, Gokaslan S, Topaloglu S
INTRODUCTION: The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc).
OBJECTIVES: We investigated the predictive value of lymphocyte to monocyte ratio (LMR) for mortality in first 30 days after APE.
METHODS: The study population included 264 APE patients of which 230 patients were survivors, 34 patients were non-survivors.
RESULTS: LMR was significantly lower in non-survivors after APE (P < .001). Neutrophil-to-lymphocyte ratio (NLR) was higher in non-survivors after APE (P < .001). Platelet-to-lymphocyte (PLR) had no significance between both groups (P: .241). Simplified pulmonary embolism severity index and LMR were independent predictors of mortality in patients with APE (P: .008 and P: .001, respectively).
CONCLUSION: LMR as a novel marker of inflammation seemed to be an independent predictor of short-term mortality in patients with APE.
PMID: 27727508 [PubMed - indexed for MEDLINE]