Euglisemic diabetic ketoacidotic coma caused by dapagliflozin.
Am J Emerg Med. 2018 Aug 21;:
Authors: Karakaya Z, Topal FE, Topal F, Payza U, Akyol PY
Diabetic ketoacidosis (DKA) is a serious and potentially life-threatening acute complication of diabetes mellitus (DM). Sodium-glucose co-transporter-2(SGLT-2) inhibitors are new orally administered antihyperglycemic agents. These agents are related with rarely seen euglycemic diabetic ketoacidosis (eDKA) cases, which are difficult to diagnose in emergency department (ED) because of absence of an evident hyperglycemia and may result with potentially dangerous outcomes if missed. In this study, we present a clinical case of a patient, admitted to ED with altered mental status after SGLT2 inhibitor dapagliflozin administration.
PMID: 30150107 [PubMed - as supplied by publisher]