Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics.
JAMA. 2018 Jul 19;:
Authors: Goldenberg JZ, Mertz D, Johnston BC
Clinical Question: In adults and children prescribed antibiotics, is co-administration of a probiotic associated with a lower risk of symptomatic Clostridium difficile infection without an increase in adverse events?
Bottom Line: Moderate-quality evidence suggests that probiotics are associated with a lower risk of C difficile infection and very low-quality evidence suggests that probiotics are associated with fewer adverse events vs placebo or no treatment.
PMID: 30027207 [PubMed - as supplied by publisher]