Clinical narrative: autoimmune hepatitis.

Link to article at PubMed

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Clinical narrative: autoimmune hepatitis.

Am J Gastroenterol. 2018 May 14;:

Authors: Schmeltzer PA, Russo MW

Autoimmune hepatitis (AIH) is an inflammatory liver disease that is characterized by circulating autoantibodies, hypergammaglobulinemia, and a lymphoplasmocytic infiltration with interface hepatitis on liver biopsy. Treatment with corticosteroids and other immunosuppressive agents is effective and early diagnosis can result in near-normal life expectancy. Untreated patients, however, can progress to cirrhosis and liver failure. The clinical presentation is heterogeneous and may pose diagnostic and therapeutic dilemmas. This case-based review will address the diagnosis and management of this disease, in addition to difficult but commonly encountered clinical scenarios.

PMID: 29755125 [PubMed - as supplied by publisher]

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